As you probably know, OPC (see more at the OPC Foundation, here)
is a standard for exchanging data in industrial automation. Commonly used in
the process industries by DCS, SCADA, and data historian systems, it also has
some very interesting benefits when combined with a process simulator.

You'll need to spend a little more effort to ensure that you have a validated model of your process (the simulation matches your plant performance within a tolerance you're comfortable with, and it reacts to process changes correctly). Many of you already go to this level of detail with your "offline" use of simulation software.
Imagine having alarms built into your SCADA system that can alert operations staff to deviations in plant performance versus design specifications! There are even installations of advanced process control (APC) using rigorous CHEMCAD simulations to improve process efficiency by linking SCADA systems, simulations, and economic optimization engines.
We’ve helped many customers do all of the above and more, so
give our support team a call if you’re thinking about a project and want to
understand CHEMCAD’s OPC Server capabilities.
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